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  1. Research article

    αT-catenin in restricted brain cell types and its potential connection to autism

    Recent genetic association studies have linked the cadherin-based adherens junction protein alpha-T-catenin (αT-cat, CTNNA3) with the development of autism. Where αT-cat is expressed in the brain, and how its los...

    Stephen Sai Folmsbee, Douglas R. Wilcox, Koen Tyberghein, Pieter De Bleser, Warren G. Tourtellotte, Jolanda van Hengel, Frans van Roy and Cara J. Gottardi

    Journal of Molecular Psychiatry 2016 4:2

    Published on: 21 June 2016

  2. Short report

    De novo POGZ mutations in sporadic autism disrupt the DNA-binding activity of POGZ

    A spontaneous de novo mutation is a new mutation appeared in a child that neither the parent carries. Recent studies suggest that recurrent de novo loss-of-function mutations identified in patients with sporad...

    Kensuke Matsumura, Takanobu Nakazawa, Kazuki Nagayasu, Nanaka Gotoda-Nishimura, Atsushi Kasai, Atsuko Hayata-Takano, Norihito Shintani, Hidenaga Yamamori, Yuka Yasuda, Ryota Hashimoto and Hitoshi Hashimoto

    Journal of Molecular Psychiatry 2016 4:1

    Published on: 21 April 2016

  3. Research article

    Prevalence of mental distress and associated factors among caregivers of patients with severe mental illness in the outpatient unit of Amanuel Hospital, Addis Ababa, Ethiopia, 2013: Cross-sectional study

    Caregivers like family members or other relatives are central and provide not only practical help and personal care but also give emotional support, and they are suffering from plenty of challengeable tasks. T...

    Mezinew Sintayehu, Haregwoin Mulat, Zegeye Yohannis, Tewodros Adera and Maereg Fekade

    Journal of Molecular Psychiatry 2015 3:9

    Published on: 8 October 2015

  4. Research article

    Preparation for teacher collaboration in inclusive classrooms – stress reduction for special education students via acceptance and commitment training: A controlled study

    The education system in Germany is beginning to witness a sea change, lately, owing to the country’s ratification of the United Nation’s Convention on the Rights of Persons with Disabilities. The enactment is ...

    Simone Pülschen and Dietrich Pülschen

    Journal of Molecular Psychiatry 2015 3:8

    Published on: 28 September 2015

  5. Research article

    Insights into the origin of DNA methylation differences between monozygotic twins discordant for schizophrenia

    DNA methylation differences between monozygotic twins discordant for schizophrenia have been previously reported. However, the origin of methylation differences between monozygotic twins discordant for schizop...

    Melkaye G. Melka, Christina A. Castellani, Richard O’Reilly and Shiva M. Singh

    Journal of Molecular Psychiatry 2015 3:7

    Published on: 26 June 2015

  6. Research article

    Characterization of cognitive deficits in spontaneously hypertensive rats, accompanied by brain insulin receptor dysfunction

    The spontaneously hypertensive rat (SHR) has been used to model changes in the central nervous system associated with cognitive-related disorders. Recent human and animal studies indicate a possible relationsh...

    Edna Grünblatt, Jasmin Bartl, Diana-Iulia Iuhos, Ana Knezovic, Vladimir Trkulja, Peter Riederer, Susanne Walitza and Melita Salkovic-Petrisic

    Journal of Molecular Psychiatry 2015 3:6

    Published on: 4 June 2015

  7. Review

    Behavioral disorders and cognitive impairment associated with cerebellar lesions

    In the last decade evidence has accumulated that suggests that the cerebellum is involved not only in motor but also in behavioral and cognitive functions. A myriad of anatomical, clinical and imaging studies ...

    Stefan Grossauer, Katharina Koeck, Thomas Kau, Joerg Weber and Giles H Vince

    Journal of Molecular Psychiatry 2015 3:5

    Published on: 15 May 2015

  8. Review

    A systematic review of agomelatine-induced liver injury

    Agomelatine is an antidepressant with a unique mechanism of action. Since its marketing in 2009, concerns have been raised regarding its potential to induce liver injury. The authors therefore address the need...

    Silka Dawn Freiesleben and Karolina Furczyk

    Journal of Molecular Psychiatry 2015 3:4

    Published on: 21 April 2015

  9. Research article

    Metabolite profiling in posttraumatic stress disorder

    Traumatic stress does not only increase the risk for posttraumatic stress disorder (PTSD), but is also associated with adverse secondary physical health outcomes. Despite increasing efforts, we only begin to u...

    Alexander Karabatsiakis, Gilava Hamuni, Sarah Wilker, Stephan Kolassa, Durairaj Renu, Suzanne Kadereit, Maggie Schauer, Thomas Hennessy and Iris-Tatjana Kolassa

    Journal of Molecular Psychiatry 2015 3:2

    Published on: 8 February 2015

  10. Research article

    Mitochondrial complex I and III gene mRNA levels in schizophrenia, and their relationship with clinical features

    The etiology of schizophrenia is not precisely known; however, mitochondrial function and cerebral energy metabolism abnormalities were determined to be possible factors associated with the etiology of schizop...

    Süleyman Akarsu, Deniz Torun, Abdullah Bolu, Murat Erdem, Salih Kozan, Mehmet Ak, Hatice Akar and Özcan Uzun

    Journal of Molecular Psychiatry 2014 2:6

    Published on: 10 December 2014

  11. Review

    Sluggish cognitive tempo and its neurocognitive, social and emotive correlates: a systematic review of the current literature

    Since the elimination of items associated with Sluggish Cognitive Tempo (SCT) during the transition from DSM-III to DSM-IV from the diagnostic criteria of Attention-deficit Hyperactivity Disorder (ADHD), inter...

    Anna Katharina Mueller, Lara Tucha, Janneke Koerts, Yvonne Groen, Klaus W Lange and Oliver Tucha

    Journal of Molecular Psychiatry 2014 2:5

    Published on: 5 August 2014

  12. Review

    The relationship between irritable bowel syndrome and psychiatric disorders: from molecular changes to clinical manifestations

    Irritable bowel syndrome (IBS) is a functional syndrome characterized by chronic abdominal pain accompanied by altered bowel habits. Although generally considered a functional disorder, there is now substantia...

    Mihaela Fadgyas-Stanculete, Ana-Maria Buga, Aurel Popa-Wagner and Dan L Dumitrascu

    Journal of Molecular Psychiatry 2014 2:4

    Published on: 27 June 2014

  13. Review

    HIV-associated neurocognitive disorders

    Currently, neuropsychological impairment among HIV+ patients on antiretroviral therapy leads to a reduction in the quality of life and it is an important challenge due to the high prevalence of HIV-associated ...

    Montserrat Sanmarti, Laura Ibáñez, Sonia Huertas, Dolors Badenes, David Dalmau, Mark Slevin, Jerzy Krupinski, Aurel Popa-Wagner and Angeles Jaen

    Journal of Molecular Psychiatry 2014 2:2

    Published on: 4 March 2014

  14. Research article

    Association study in siblings and case-controls of serotonin- and oxytocin-related genes with high functioning autism

    Autism spectrum disorder (ASD) is heritable and neurodevelopmental with unknown causes. The serotonergic and oxytocinergic systems are of interest in autism for several reasons: (i) Both systems are implicated...

    Johanna Nyffeler, Susanne Walitza, Elise Bobrowski, Ronnie Gundelfinger and Edna Grünblatt

    Journal of Molecular Psychiatry 2014 2:1

    Published on: 24 January 2014

  15. Research article

    Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels

    The neurotrophins brain-derived neurotrophic factor (BDNF) and neurotrophic factor 3 (NT3) could play a role in addictive behavior. Interactions between BDNF and dopamine transmission influence the alcohol int...

    Aurel Popa-Wagner, Karolina Furczyk, Joerg Richter, Gisela Irmisch and Johannes Thome

    Journal of Molecular Psychiatry 2013 1:20

    Published on: 2 December 2013

  16. Research article

    Olanzapine induced DNA methylation changes support the dopamine hypothesis of psychosis

    The dopamine (DA) hypothesis of schizophrenia proposes the mental illness is caused by excessive transmission of dopamine in selected brain regions. Multiple lines of evidence, including blockage of dopamine r...

    Melkaye G Melka, Christina A Castellani, Benjamin I Laufer, N Rajakumar, Richard O’Reilly and Shiva M Singh

    Journal of Molecular Psychiatry 2013 1:19

    Published on: 4 November 2013

  17. Review

    The nucleus accumbens: a target for deep brain stimulation in resistant major depressive disorder

    This review aimed to investigate the therapeutic potential of Deep Brain Stimulation (DBS) for treating resistant Major Depressive Disorder (MDD). We explored the role of Nucleus accumbens (Nac) as a target fo...

    Cecilia Nauczyciel, Suzanne Robic, Thibaut Dondaine, Marc Verin, Gabriel Robert, Dominique Drapier, Florian Naudet and Bruno Millet

    Journal of Molecular Psychiatry 2013 1:17

    Published on: 23 October 2013

  18. Review

    Matrix metalloproteinases in autism spectrum disorders

    Autism Spectrum Disorders (ASD) are group of developmental disabilities with a complex neurobiological basis including putative changes in the immune system. They are characterized by pervasive qualitative abn...

    Morsi W Abdallah and Tanja M Michel

    Journal of Molecular Psychiatry 2013 1:16

    Published on: 17 September 2013

  19. Research article

    Elevated oleic acid serum concentrations in patients suffering from alcohol dependence

    Alcohol-induced damages such as brain atrophy and fatty liver are closely related to a disturbed lipid metabolism. In animal models, a linkage between chronic alcohol consumption and changes in fatty acid (FA)...

    Annekatrin Teubert, Johannes Thome, Andreas Büttner, Jörg Richter and Gisela Irmisch

    Journal of Molecular Psychiatry 2013 1:13

    Published on: 23 August 2013

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