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Table 1 Locomotor activity (average number of beam breaks/5 minutes ± stderr) of olanzapine treated rats and their matched-controls during day 0 and 21 as measured baseline (before stress) and post-stress (n = 8 per each group)

From: Olanzapine induced DNA methylation changes support the dopamine hypothesis of psychosis

 

Day 0 baseline

Day 0 post-stress

Day 21 baseline

Day 21 post-stress

Control

22.0 ± 2.64

101.9 ± 4.00

17.1 ± 2.47

85.6 ± 7.28

Olanzapine

22.0 ± 2.65

94.7 ± 6.54

16.9 ± 2.67

32.6 ± 4.42

p-values

1

0.452

0.973

0.001

  1. T-test was used to compute the significance of differences between olanzapine treated and control groups.
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Journal of Molecular Psychiatry

ISSN: 2049-9256

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