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Table 4 Changes in neural plasticity in suicide

From: The neurobiology of suicide - A Review of post-mortem studies

System element

  

Change

Location

Neurotrophic factors

Neurotrophins

BDNF level

decreased

PFC, HIP,antidepressants-free subjects

 

NT-3 level

decreased

PFC, HIP, antidepressants-free subjects

BDNF-binding receptor

TrkB receptor concentration

decreased

PFC, HIP

TrkB.T1 truncated form receptor concentration

decreased

PFC

Polyamins

Putrescine levels

increased

G

 

Spermidine levels

increased

G