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Table 5 HPA axis in suicide

From: The neurobiology of suicide - A Review of post-mortem studies

System element Change Location
Hormones CRH levels increased LC, DLPFC, FPC, VMPFC, CN
decreased DVC
POMC mRNA level increased aPIT
Receptors CRH-receptors receptor density decreased FC
CRH1-receptor mRNA level decreased G CRH1-receptor mRNA level
  CRH1/CRH2receptor ratio decreased PIT CRH1/CRH2receptor ratio