Table 5 HPA axis in suicide
From: The neurobiology of suicide - A Review of post-mortem studies
System element | Change | Location | ||
|---|---|---|---|---|
Hormones | CRH levels | increased | LC, DLPFC, FPC, VMPFC, CN | |
decreased | DVC | |||
POMC mRNA level | increased | aPIT | ||
Receptors | CRH-receptors | receptor density | decreased | FC |
CRH1-receptor mRNA level | decreased | G | CRH1-receptor mRNA level | |
| Â | CRH1/CRH2receptor ratio | decreased | PIT | CRH1/CRH2receptor ratio |