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Table 2 Genotype distribution, genotype frequencies, and minor allele frequencies for autism spectrum disorder (ASD), siblings, and control groups

From: Association study in siblings and case-controls of serotonin- and oxytocin-related genes with high functioning autism

Polymorphism

Genotype distribution (Genotype frequency)

MAF (Allele)

HTTLPR triallelic 1

ss

sl

ll

 

ASD

24 (0.316)

38 (0.500)

14 (0.184)

0.434 (l)

Siblings

16 (0.208)

43 (0.558)

18 (0.234)

0.487 (s)

Controls

22 (0.248)

51 (0.526)

24 (0.247)

0.490 (s)

HTR2A rs6311 2

GG

GA

AA

A

ASD

21 (0.276)

34 (0.447)

21 (0.276)

0.500

Siblings

23 (0.295)

35 (0.449)

20 (0.256)

0.481

Controls

29 (0.299)

47 (0.485)

21 (0.216)

0.459

OXTR rs2301261

CC

CT

TT

T

ASD

65 (0.855)

11 (0.145)

0

0.072

Siblings

67 (0.859)

11 (0.141)

0

0.071

Controls

84 (0.848)

15 (0.152)

0

0.076

OXTR rs53576 1

AA

AG

GG

A

ASD

7 (0.092)

34 (0.447)

35 (0.461)

0.316

Siblings

7 (0.091)

37 (0.481)

33 (0.429)

0.331

Controls

9 (0.093)

33 (0.340)

55 (0.567)

0.263

OXTR rs2254298

AA

AG

GG

A

ASD

0

12 (0.158)

64 (0.842)

0.079

Siblings

0

13 (0.167)

65 (0.833)

0.083

Controls

0

21 (0.212)

78 (0.788)

0.106

OXTR rs2268494

AA

AT

TT

A

ASD

0

13 (0.171)

63 (0.829)

0.086

Siblings

1 (0.013)

9 (0.115)

68 (0.872)

0.071

Controls

0

17 (0.172)

82 (0.828)

0.086

  1. Abbreviations: ASD autism spectrum disorder, OXTR oxytocin receptor, HTR2A serotonin receptor 2A, HTTLPR serotonin-transporter–linked polymorphic region, MAF minor allele frequency. 1Genotyping failed repeatedly for one sibling and two controls. 2Genotyping failed repeatedly for two controls.