| |
p values
|
|---|
|
Polymorphism
|
AA vs. controls
|
AS vs. controls
|
ASD vs. controls
|
ASD vs. siblings
|
|---|
|
Genotype frequencies
| | | | |
|
HTTLPR triallelic
|
0.926
|
0.110
|
0.350
|
0.301
|
|
HTR2A rs6311
|
0.720
|
0.299
|
0.661
|
0.949
|
|
OXTR rs2301261
|
0.595
|
0.731
|
0.901
|
0.948
|
|
OXTR rs53576
|
0.524
|
0.280
|
0.334
|
0.914
|
|
OXTR rs2254298
|
0.460
|
0.592
|
0.363
|
0.883
|
|
OXTR rs2268494
|
0.870
|
0.974
|
0.991
|
0.388
|
|
Allele frequencies
| | | | |
|
HTTLPR triallelic
|
0.708
|
0.040
|
0.160
|
0.168
|
|
HTR2A rs6311
|
0.591
|
0.410
|
0.446
|
0.736
|
|
OXTR rs2301261
|
0.609
|
0.743
|
0.905
|
0.950
|
|
OXTR rs53576
|
0.307
|
0.464
|
0.280
|
0.774
|
|
OXTR rs2254298
|
0.486
|
0.614
|
0.390
|
0.888
|
|
OXTR rs2268494
|
0.877
|
0.975
|
0.991
|
0.623
|
|
Carrier frequencies [Carrier]
| | | | |
|
HTTLPR triallelic [s]
|
0.787
|
0.108
|
0.319
|
0.451
|
|
HTTLPR triallelic [l]
|
0.725
|
0.073
|
0.189
|
0.129
|
|
HTR2A rs6311 [C]
|
0.949
|
0.158
|
0.362
|
0.780
|
|
HTR2A rs6311 [T]
|
0.433
|
0.948
|
0.744
|
0.799
|
|
OXTR rs53576 [G]
|
0.776
|
0.579
|
0.988
|
0.980
|
|
OXTR rs53576 [A]
|
0.258
|
0.216
|
0.164
|
0.691
|
- In the subgroup analysis the three childhood autism were not included in either AA or AS subgroup. Abbreviations: AA atypical autism, AS Asperger syndrome, ASD autism spectrum disorder, OXTR oxytocin receptor, HTR2A serotonin receptor 2A, HTTLPR serotonin-transporter–linked polymorphic region, vs. versus, Bold nominal significant.
