|
NGF
|
Nerve growth factor
|
Pro-inflammatory mediator; psychoneuroendocrine modulator
|
Overexpression (in rat model)
|
Anxiety, chronic alcohol consumption, depression
|
[71, 72]
|
|
BDNF
|
Brain-Derived Neurotrophic Factor
|
Regulation of stress response and in the biology of mood disorders
|
SNP
|
Psychiatric IBS, schizophrenia, mood disorders, PTSD
|
[73, 74]
|
|
COMT
|
Catechol
|
Degradative pathways of the catecholamine transmitters; metabolism of catechol drugs
|
SNP
|
Anxiety, panic disorder, and cognitive performance
|
[75, 76]
|
|
O-Methyltransferase
|
|
OPRM1
|
Mu Opiate Receptor
|
Principal target of endogenous opioid peptides
|
SNP
|
Pain sensitivity, opioid dependence, and social sensitivity
|
[77, 78]
|
|
5-HTTLPR
|
5-hydroxytryptamine transporter gene-linked polymorphic region
|
Serotonin transporter
|
SNP
|
Depression, anxiety, rectal pain ratings
|
[79, 80]
|
