Mitochondrial complex I and III gene mRNA levels in schizophrenia, and their relationship with clinical features

Table 1 Clinical characteristics of schizophrenia cases

Variables	Groups		Statistical analysis
	First-episode schizophrenia (n = 54)	Chronic schizophrenia (n = 84)	Statistical analysis
Duration of disease; Mean ± s.d (month)	0.2 ± 0.1	32.2 ± 17.6	Z = −8.8; p < 0.01
Age of onset of the disease; Mean ± s.d (year)	21.6 ± 1.5	20.2 ± 1.7	Z = −3.8; p < 0.01
Duration of hospitalization; Mean ± s.d (day)	18.3 ± 3.5	14.4 ± 2.8	Z = −5.1; p < 0.01
SANS; Mean ± s.d	46.9 ± 11.9	48.2 ± 12.4	Z = −0.6; p = 0.55
SAPS; Mean ± s.d	58.7 ± 17.6	39.2 ± 21.9	Z = −4.1; p < 0.01
BPRS; Mean ± s.d	40.7 ± 9.4	31.0 ± 9.7	Z = −4.5; p < 0.01

Mean ± s.d : Mean ± standart deviation Z: Mann–Whitney U test.
No statistically significant difference was detected between first-episode schizophrenia and chronic schizophrenia in terms of SANS score (p = 0.55). SAPS (p < 0.01) and BPRS (p < 0.01) scores were higher in first-episode schizophrenia cases. The age of onset of the disease was higher in first-episode schizophrenia (p < 0.01). Duration of hospitalization was longer in patients with first-episode schizophrenia cases than chronic schizophrenia cases (p < 0.01).

ISSN: 2049-9256