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Table 2 Gene mRNA levels of the cases

From: Mitochondrial complex I and III gene mRNA levels in schizophrenia, and their relationship with clinical features

Variables First episode schizophrenia (n = 54) Chronic schizophrenia (n = 84) Control (n = 42) First episode vs chronic p First episode vs control p Cronic vs control p
NDUFV1; Mean ± s.d 1.6 ± 1.3 1.3 ± 1.0 1.0 ± 0.0 Z = −1.7; 0.09 Z = −3.0; 0.003* Z = −1.4; 0.2
NDUFV2; Mean ± s.d 2.0 ± 1.6 1.8 ± 1.5 1.0 ± 0.0 Z = −1.1; 0.28 Z = −5.0; < 0.01* Z = −4.2; < 0.01*
NDUFS1; Mean ± s.d 1.6 ± 0.9 1.5 ± 1.0 1.0 ± 0.0 Z = −1.0; 0.32 Z = −3.0; 0.003* Z = −2.8; 0,07
UQCR10; Mean ± s.d 5.7 ± 13.0 5.6 ± 17.5 1.0 ± 0.0 Z = −0.2; 0.82 Z = −6.7; 0.5 Z = −1.4; 0.2
  1. Mean ± s.d: Mean ± standart deviation *p < 0.05 Z: Mann–Whitney U test.
  2. mRNA levels of NDUFV1 were significantly higher in first-episode schizophrenia cases than control subjects (p = 0.003). mRNA levels of NDUFV2 were significantly higher in first-episode schizophrenia (p < 0.01) and chronic schizophrenia (p < 0.01) cases than control subjects. mRNA levels of NDUFS1 were significantly higher in first-episode schizophrenia cases than control subjects (p = 0.003).