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Table 3 mRNA levels of the genes in schizophrenia subtypes

From: Mitochondrial complex I and III gene mRNA levels in schizophrenia, and their relationship with clinical features

Variables Paranoid (n = 32) pa Catatonic (n = 17) pa Disorganized (n = 39) pa Undifferentiated (n = 26) pa Residual (n = 24) pa Statistical analysis
NDUFV1; Mean ± s.d 1.4 ± 1.3 0.5 1.6 ± 0.7 0.01 1.7 ± 1.6 0.02 1.5 ± 1.2 0.02 1.3 ± 0.6 0.08 X 2 = 3.50; df = 2; p = 0.5
NDUFV2; Mean ± s.d 1.6 ± 1.2 0.2 2.1 ± 0.9 < 0.01 2.4 ± 1.9 < 0.01 1.7 ± 1.1 0.02 1.6 ± 1.8 0.1 X 2 = 5.48; df = 2; p = 0.2
NDUFS1; Mean ± s.d 1.3 ± 0.8 0.4 1.9 ± 1.0 0.01 1.7 ± 0.8 0.01 1.6 ± 0.7 < 0.01 1.5 ± 1.2 0,.2 X 2 = 4.10; df = 2; p = 0.4
UQCR10; Mean ± s.d 5.6 ± 13.5 0.6 12.9 ± 21.5 0.1 2.6 ± 4.2 0.7 1.8 ± 2.2 0.7 9.7 ± 24.8 0.2 X 2 = 2.5; df = 2; p = 0.6
  1. Mean ± s.d: Mean ± standart deviation X2: Kruskal Wallis test pa : Compared with control group.
  2. There was no significant difference in mRNA levels of schizophrenia subtypes. mRNA levels of complex I genes (NDUFV1, NDUFV2, NDUFS1) in catatonic, disorganized and undifferentiated types were significantly higher than control group.