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Fig. 1 | Journal of Molecular Psychiatry

Fig. 1

From: Characterization of cognitive deficits in spontaneously hypertensive rats, accompanied by brain insulin receptor dysfunction

Fig. 1

Results of Morris Water Maze probe trial and Passive Avoidance test in spontaneously hypertensive rats. Results are shown for 3- and 7-month-old female (a, b, c) animals. Morris Water Maze (MWM) test–probe trial results: a time spent swimming within the targeted quadrant; b number of entries into the wrong quadrant (mistakes). Passive avoidance test (PAT) results: c latency time. Line in the boxes represent the median, whiskers are the 10 and 90 % percentile. Female spontaneously hypertensive rats (SHR) = White box; Female Wistar Kyoto control rats (WKY) = Grey box. Significant differences were based on the ANOVA Post-Hoc Scheffé; *p < 0.0001 vs. controls; **p < 0.05; T (tendency) 0.05 < p < 0.1; n = 10

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