Fig. 1
From: αT-catenin in restricted brain cell types and its potential connection to autism
αT-cat is localized to ependymal, but not choroid plexus, epithelial cell junctions. a Double immunofluorescence labeling of the perihippocampal third ventricle of WT and αT-cat KO mice with antibodies to either αT-cat or αE-cat. αE-cat is found in both ependymal (EP) cell-cell junctions (arrows, enlarged in white boxes) and choroid plexus (CP) (arrowheads), whereas αT-cat is detected in only ependymal cells. b Immunofluorescence of the lateral ventricle proximal to the subventricular zone of an adult human. β-catenin is found at ependymal cell-cell junctions with αT-cat (arrows). c Immunofluorescence staining of αE-cat in the anterior lateral ventricles of WT and αT-cat KO mice, quantified in (d), n = 6. Hoechst-stained nuclei in blue. *p < 0.05, Student’s t-test. Error bars = S.E.M