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Fig. 3 | Journal of Molecular Psychiatry

Fig. 3

From: αT-catenin in restricted brain cell types and its potential connection to autism

Fig. 3

Loss of αT-cat does not disrupt proliferation along the SVZ. a Immunofluorescence of the lateral ventricle subventricular zone (SVZ) for Ki-67, indicating similar regions of proliferation (arrows) between WT and αT-cat KO mice. b Immunofluorescence of doublecortin (Dcx) along the walls (arrows) of lateral ventricle SVZ. c Quantification of total Ki-67-positive cells along the WT and αT-cat KO mice SVZ (n = 4), with no significant difference by Student’s t-test. d Western blot of Dcx in whole brain lysate (below) of WT and KO mice (n = 4), with tubulin as a loading control. e Immunofluorescence of focal regions of the lateral ventricle subventricular zone (SVZ) for Tuj1 (green, immature neurons) and GFAP (red, glial cells) of WT and αT-cat KO mice.). n.s. = not significant. Hoechst-stained nuclei in blue

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