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Fig. 6 | Journal of Molecular Psychiatry

Fig. 6

From: αT-catenin in restricted brain cell types and its potential connection to autism

Fig. 6

αT-cat is not present in the cerebral cortex, but rather is in the molecular layer of the cerebellum. a Western blot of whole brain lysate of WT and αT-cat KO mice. b-c Western blot of cerebral cortex and cerebella, dissected without nearby ventricles, of WT and αT-cat KO mice. d Immunofluorescence of αT-cat in the cerebral cortex and cerebellum in WT and αT-cat KO mice, with false positive signal (arrows) and true positive signal in the molecular layer and pia mater (arrowheads) of the cerebellum (bottom panels). e Double immunofluorescence of αT-cat and αE-cat in human cerebellum, with positive αT-cat staining (arrowheads) in the molecular layer. Hoechst-stained nuclei in blue

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