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Journal of Molecular Psychiatry

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  1. Content type: Research article

    Recent genetic association studies have linked the cadherin-based adherens junction protein alpha-T-catenin (αT-cat, CTNNA3) with the development of autism. Where αT-cat is expressed in the brain, and how its los...

    Authors: Stephen Sai Folmsbee, Douglas R. Wilcox, Koen Tyberghein, Pieter De Bleser, Warren G. Tourtellotte, Jolanda van Hengel, Frans van Roy and Cara J. Gottardi

    Citation: Journal of Molecular Psychiatry 2016 4:2

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  2. Content type: Short report

    A spontaneous de novo mutation is a new mutation appeared in a child that neither the parent carries. Recent studies suggest that recurrent de novo loss-of-function mutations identified in patients with sporad...

    Authors: Kensuke Matsumura, Takanobu Nakazawa, Kazuki Nagayasu, Nanaka Gotoda-Nishimura, Atsushi Kasai, Atsuko Hayata-Takano, Norihito Shintani, Hidenaga Yamamori, Yuka Yasuda, Ryota Hashimoto and Hitoshi Hashimoto

    Citation: Journal of Molecular Psychiatry 2016 4:1

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  3. Content type: Research article

    Caregivers like family members or other relatives are central and provide not only practical help and personal care but also give emotional support, and they are suffering from plenty of challengeable tasks. T...

    Authors: Mezinew Sintayehu, Haregwoin Mulat, Zegeye Yohannis, Tewodros Adera and Maereg Fekade

    Citation: Journal of Molecular Psychiatry 2015 3:9

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  4. Content type: Research article

    The education system in Germany is beginning to witness a sea change, lately, owing to the country’s ratification of the United Nation’s Convention on the Rights of Persons with Disabilities. The enactment is ...

    Authors: Simone Pülschen and Dietrich Pülschen

    Citation: Journal of Molecular Psychiatry 2015 3:8

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  5. Content type: Research article

    DNA methylation differences between monozygotic twins discordant for schizophrenia have been previously reported. However, the origin of methylation differences between monozygotic twins discordant for schizop...

    Authors: Melkaye G. Melka, Christina A. Castellani, Richard O’Reilly and Shiva M. Singh

    Citation: Journal of Molecular Psychiatry 2015 3:7

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  6. Content type: Research article

    The spontaneously hypertensive rat (SHR) has been used to model changes in the central nervous system associated with cognitive-related disorders. Recent human and animal studies indicate a possible relationsh...

    Authors: Edna Grünblatt, Jasmin Bartl, Diana-Iulia Iuhos, Ana Knezovic, Vladimir Trkulja, Peter Riederer, Susanne Walitza and Melita Salkovic-Petrisic

    Citation: Journal of Molecular Psychiatry 2015 3:6

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  7. Content type: Review

    In the last decade evidence has accumulated that suggests that the cerebellum is involved not only in motor but also in behavioral and cognitive functions. A myriad of anatomical, clinical and imaging studies ...

    Authors: Stefan Grossauer, Katharina Koeck, Thomas Kau, Joerg Weber and Giles H Vince

    Citation: Journal of Molecular Psychiatry 2015 3:5

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  8. Content type: Review

    Agomelatine is an antidepressant with a unique mechanism of action. Since its marketing in 2009, concerns have been raised regarding its potential to induce liver injury. The authors therefore address the need...

    Authors: Silka Dawn Freiesleben and Karolina Furczyk

    Citation: Journal of Molecular Psychiatry 2015 3:4

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  9. Content type: Review

    Pathologies of central nervous system (CNS) functions are involved in prevalent conditions such as Alzheimer’s disease, depression, and Parkinson’s disease. Notable pathologies include dysfunctions of circadia...

    Authors: Julie A Morgan, Frances Corrigan and Bernhard T Baune

    Citation: Journal of Molecular Psychiatry 2015 3:3

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  10. Content type: Research article

    Traumatic stress does not only increase the risk for posttraumatic stress disorder (PTSD), but is also associated with adverse secondary physical health outcomes. Despite increasing efforts, we only begin to u...

    Authors: Alexander Karabatsiakis, Gilava Hamuni, Sarah Wilker, Stephan Kolassa, Durairaj Renu, Suzanne Kadereit, Maggie Schauer, Thomas Hennessy and Iris-Tatjana Kolassa

    Citation: Journal of Molecular Psychiatry 2015 3:2

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  11. Content type: Research article

    The etiology of schizophrenia is not precisely known; however, mitochondrial function and cerebral energy metabolism abnormalities were determined to be possible factors associated with the etiology of schizop...

    Authors: Süleyman Akarsu, Deniz Torun, Abdullah Bolu, Murat Erdem, Salih Kozan, Mehmet Ak, Hatice Akar and Özcan Uzun

    Citation: Journal of Molecular Psychiatry 2014 2:6

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  12. Content type: Review

    Since the elimination of items associated with Sluggish Cognitive Tempo (SCT) during the transition from DSM-III to DSM-IV from the diagnostic criteria of Attention-deficit Hyperactivity Disorder (ADHD), inter...

    Authors: Anna Katharina Mueller, Lara Tucha, Janneke Koerts, Yvonne Groen, Klaus W Lange and Oliver Tucha

    Citation: Journal of Molecular Psychiatry 2014 2:5

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  13. Content type: Review

    Irritable bowel syndrome (IBS) is a functional syndrome characterized by chronic abdominal pain accompanied by altered bowel habits. Although generally considered a functional disorder, there is now substantia...

    Authors: Mihaela Fadgyas-Stanculete, Ana-Maria Buga, Aurel Popa-Wagner and Dan L Dumitrascu

    Citation: Journal of Molecular Psychiatry 2014 2:4

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  14. Content type: Review

    Currently, neuropsychological impairment among HIV+ patients on antiretroviral therapy leads to a reduction in the quality of life and it is an important challenge due to the high prevalence of HIV-associated ...

    Authors: Montserrat Sanmarti, Laura Ibáñez, Sonia Huertas, Dolors Badenes, David Dalmau, Mark Slevin, Jerzy Krupinski, Aurel Popa-Wagner and Angeles Jaen

    Citation: Journal of Molecular Psychiatry 2014 2:2

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  15. Content type: Research article

    Autism spectrum disorder (ASD) is heritable and neurodevelopmental with unknown causes. The serotonergic and oxytocinergic systems are of interest in autism for several reasons: (i) Both systems are implicated...

    Authors: Johanna Nyffeler, Susanne Walitza, Elise Bobrowski, Ronnie Gundelfinger and Edna Grünblatt

    Citation: Journal of Molecular Psychiatry 2014 2:1

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  16. Content type: Research article

    The neurotrophins brain-derived neurotrophic factor (BDNF) and neurotrophic factor 3 (NT3) could play a role in addictive behavior. Interactions between BDNF and dopamine transmission influence the alcohol int...

    Authors: Aurel Popa-Wagner, Karolina Furczyk, Joerg Richter, Gisela Irmisch and Johannes Thome

    Citation: Journal of Molecular Psychiatry 2013 1:20

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  17. Content type: Research article

    The dopamine (DA) hypothesis of schizophrenia proposes the mental illness is caused by excessive transmission of dopamine in selected brain regions. Multiple lines of evidence, including blockage of dopamine r...

    Authors: Melkaye G Melka, Christina A Castellani, Benjamin I Laufer, N Rajakumar, Richard O’Reilly and Shiva M Singh

    Citation: Journal of Molecular Psychiatry 2013 1:19

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  18. Content type: Review

    This review aimed to investigate the therapeutic potential of Deep Brain Stimulation (DBS) for treating resistant Major Depressive Disorder (MDD). We explored the role of Nucleus accumbens (Nac) as a target fo...

    Authors: Cecilia Nauczyciel, Suzanne Robic, Thibaut Dondaine, Marc Verin, Gabriel Robert, Dominique Drapier, Florian Naudet and Bruno Millet

    Citation: Journal of Molecular Psychiatry 2013 1:17

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  19. Content type: Review

    Autism Spectrum Disorders (ASD) are group of developmental disabilities with a complex neurobiological basis including putative changes in the immune system. They are characterized by pervasive qualitative abn...

    Authors: Morsi W Abdallah and Tanja M Michel

    Citation: Journal of Molecular Psychiatry 2013 1:16

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  20. Content type: Research article

    Depression is a prevalent neuropsychiatric disorder that affects an estimated 350 million people worldwide. Currently available treatments for depression are lacking in both speed of onset and efficacy. Recent...

    Authors: Jason M Dwyer, Ashley E Lepack and Ronald S Duman

    Citation: Journal of Molecular Psychiatry 2013 1:15

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  21. Content type: Research article

    Alcohol-induced damages such as brain atrophy and fatty liver are closely related to a disturbed lipid metabolism. In animal models, a linkage between chronic alcohol consumption and changes in fatty acid (FA)...

    Authors: Annekatrin Teubert, Johannes Thome, Andreas Büttner, Jörg Richter and Gisela Irmisch

    Citation: Journal of Molecular Psychiatry 2013 1:13

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