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Table 2 Gene mRNA levels of the cases

From: Mitochondrial complex I and III gene mRNA levels in schizophrenia, and their relationship with clinical features

Variables

First episode schizophrenia (n = 54)

Chronic schizophrenia (n = 84)

Control (n = 42)

First episode vs chronic p

First episode vs control p

Cronic

vs control p

NDUFV1; Mean ± s.d

1.6 ± 1.3

1.3 ± 1.0

1.0 ± 0.0

Z = −1.7; 0.09

Z = −3.0; 0.003*

Z = −1.4; 0.2

NDUFV2; Mean ± s.d

2.0 ± 1.6

1.8 ± 1.5

1.0 ± 0.0

Z = −1.1; 0.28

Z = −5.0; < 0.01*

Z = −4.2; < 0.01*

NDUFS1; Mean ± s.d

1.6 ± 0.9

1.5 ± 1.0

1.0 ± 0.0

Z = −1.0; 0.32

Z = −3.0; 0.003*

Z = −2.8; 0,07

UQCR10; Mean ± s.d

5.7 ± 13.0

5.6 ± 17.5

1.0 ± 0.0

Z = −0.2; 0.82

Z = −6.7; 0.5

Z = −1.4; 0.2

  1. Mean ± s.d: Mean ± standart deviation *p < 0.05 Z: Mann–Whitney U test.
  2. mRNA levels of NDUFV1 were significantly higher in first-episode schizophrenia cases than control subjects (p = 0.003). mRNA levels of NDUFV2 were significantly higher in first-episode schizophrenia (p < 0.01) and chronic schizophrenia (p < 0.01) cases than control subjects. mRNA levels of NDUFS1 were significantly higher in first-episode schizophrenia cases than control subjects (p = 0.003).